[Syllabus]: The Altered Breast

Kathleen Gundry, MD

Kathleen Gundry, MD(bio)

  • Director of Breast Imaging
  • Grady Memorial Hospital
  • Professor of Radiology and Imaging Sciences
  • Emory University School of Medicine

Introduction

This session provides a practical, imaging-focused overview of breast reduction and augmentation procedures. It covers operative techniques, expected post-operative appearances across modalities, common complications, and key imaging signs that guide diagnosis and follow-up. Emphasis is placed on mammography, ultrasound, and MRI interpretation in patients with reductions, mastopexy, and a range of implant types and positions, including recognition of benign postoperative changes versus findings that warrant closer surveillance or intervention.

Breast Reduction Surgery: Indications and Operative Techniques

Breast reduction (reduction mammaplasty) is performed for symptomatic macromastia (back/neck pain, postural changes), and for symmetry after mastectomy. Multiple incision patterns are used to remove inferior parenchyma and elevate the nipple-areolar complex (NAC).

Key Points

  • Wise pattern (keyhole/anchor): periareolar, vertical to inframammary fold (IMF), plus transverse IMF incision; most common.
  • Vertical (lollipop): periareolar plus vertical limb only; no IMF transverse scar.
  • Transverse reduction: transverse IMF incision with periareolar adjustment; no vertical limb.
  • Goal: inferior tissue resection and superior/central repositioning of NAC.

Post-Reduction Mammographic Appearances

Healing is variable; some patients exhibit minimal change while others show classic scar patterns. Recognizing characteristic post-surgical features prevents unnecessary callbacks.

Key Points

  • MLO: inferior parenchymal “swirling” or arc-like redistribution from tissue elevation.
  • CC: linear fibrous scar extending nipple-to-pectoralis and/or medial–lateral line along the IMF plane.
  • Periareolar scar: circumferential or partial ring density around NAC; may contain benign calcifications.
  • NAC position: may appear superiorly displaced postoperatively.
  • Keloids: thick, rope-like cutaneous scars may be visible.

Post-Reduction Sequelae and Management

Benign post-surgical changes overlap those seen after other breast operations. Awareness of typical timing and stability aids management.

Key Points

  • Fat necrosis: oil cysts, coarse dystrophic calcifications at surgical site; often benign when correlated with history.
  • Architectural distortion: focal dense scar with straightening/traction lines.
  • Asymmetry and displaced “islands” of parenchyma: focal tissue that appears out of normal ductal flow; assess stability over time.
  • Fluid collections: hematoma/seroma may present as evolving masses or mixed echotexture.
  • Follow-up: if uncertain early post-op, 6-month short-interval follow-up to confirm stability or resolution; resume annual screening when classic changes are present without concerning features.

Liposuction Reduction and Mastopexy: Techniques and Imaging

Liposuction can be used alone or adjunctively for contouring; ultrasound-assisted liposuction liquefies fat before aspiration. Mastopexy (breast lift) removes redundant skin (often post-pregnancy/weight change) with minimal effect on parenchyma; implants may be added.

Key Points

  • Liposuction: can yield dramatic density changes and mixed echogenic masses; hematoma and scarring may mimic pathology.
  • Mastopexy patterns: keyhole/vertical or periareolar “donut” excisions; primarily skin resection and NAC repositioning.
  • Imaging: mastopexy often shows minimal parenchymal change; may see periareolar scar/fat necrosis.

Breast Augmentation: Historical Context and Epidemiology

Augmentation methods evolved from early injections/solid materials to modern implants. Today, augmentation and post-mastectomy reconstruction are common in the U.S., with regional variability in prevalence.

Key Points

  • Early methods (paraffin, sponge, ivory, beeswax, liquid silicone injections) had high complication rates; modern implants began in the 1960s (saline in 1962; silicone gel in 1963).
  • Millions of U.S. women have implants; cosmetic and reconstructive indications account for annual growth.

Regulatory Status and Safety Considerations

Regulatory approvals and safety data inform candidacy and surveillance.

Key Points

  • FDA: silicone gel approved for augmentation ≥22 years; saline ≥18 years; both permitted at any age for reconstruction; silicone injections banned (1992).
  • Systemic disease: large reviews show no association between silicone implants and connective tissue or neurologic disease.
  • Anaplastic large cell lymphoma (ALCL): rare implant-associated cases occur in peri-implant fluid/capsule; can present years post-implantation.
  • Psychosocial: studies show increased suicide risk; causality unclear (selection vs implant effect).
  • Local complications: pain, parenchymal atrophy (with large implants), capsular contracture, malposition/asymmetry, hematoma/infection, skin/NAC necrosis, rupture.

Implant Anatomy and Materials

Understanding implant structure is foundational for imaging interpretation.

Key Points

  • Envelope: manufacturer’s outer shell containing implant filler.
  • Capsule: host-derived fibrous tissue encasing the implant; thickness varies.
  • Silicone gel: modern “gummy bear” cohesive gels are firmer, designed to limit leakage.
  • Saline: physiologic saline; valve used for intraoperative fill.

Implant Types and Their Imaging Appearance

Implant filler and construction influence modality-specific appearances.

Key Points

  • Single-lumen silicone: mammography shows dense, circumscribed ovoid; MRI shows bright silicone on silicone-specific sequences.
  • Single-lumen saline: often radiolucent on mammography; visible fill valve/folds may confirm saline; MRI T2 bright like water; valve indentation may be seen.
  • Double-lumen (silicone core, saline shell): less common; designed to sequester silicone if inner envelope fails.
  • Stacked implants: two devices layered to achieve volume/shape; dark interface line on MRI/US corresponds to adjacent envelopes.

Implant Positioning and Incisions

Position affects cosmetic results and imaging coverage; incision choice varies by surgeon and indication.

Key Points

  • Subglandular: most natural appearance; obscures more parenchyma on mammography.
  • Subpectoral (retromuscular): improves mammographic visualization; risk of pectoralis atrophy with large devices.
  • Determining position: on MLO, subpectoral shows pectoralis fibers overlying part of the implant; subglandular shows pec entirely posterior.
  • Incisions: inframammary fold (common), periareolar, transaxillary, and occasionally periumbilical approaches.

Mammography with Implants: Protocols and Limitations

Optimized technique is essential; even so, parenchymal coverage remains limited, especially with subglandular placement.

Key Points

  • Views: obtain standard CC/MLO plus implant-displaced (ID) views to maximize tissue visualization.
  • Technique: during ID views, push implant posteriorly and pull breast tissue forward; ensure AEC/detector targets breast tissue not the implant (avoid underexposure).
  • Additional views: consider a 90-degree lateral for tissue coverage if needed.
  • Reporting: note limited evaluation due to implant, particularly with subglandular placement; document implant malposition or contour abnormalities.

Ultrasound of Implants: Normal Appearances and Tips

Ultrasound complements mammography for focal symptoms and implant assessment, though silicone vs saline often looks similar.

Key Points

  • Normal: echogenic parallel lines for capsule/envelope; anechoic to hypoechoic filler with reverberation artifact; saline valve may be palpable/visible.
  • Troubleshooting: identify the implant margin and follow it to ambiguous areas to differentiate folds from pathology.
  • Newer devices: multilayer envelopes can create multiple closely apposed lines—normal finding.

MRI of Implants: Protocol and Normal Findings

MRI is the preferred modality for silicone implant integrity assessment using silicone-sensitive sequences.

Key Points

  • Technique: STIR with both fat and water saturation renders silicone bright and suppresses other tissues; T1/T2-weighted sequences provide adjunctive information.
  • Normal: bright silicone with smooth contour; thin dark capsule margin; parenchyma largely suppressed on silicone-specific sequences.

Normal Variants vs Pathology: Radial Folds and Infolding

Recognizing benign folds prevents overcalling rupture.

Key Points

  • Radial fold: thin dark line that connects to the implant surface; no silicone within the fold; seen on MRI and US.
  • Edge infolding/crenulation: subtle scalloping of contour in softer implants; benign.
  • If uncertainty persists on US, MRI can adjudicate.

Capsular Calcification and Implant Herniation

Chronic capsular reactions and focal bulges have characteristic appearances and implications.

Key Points

  • Capsular calcifications: coarse dystrophic calcifications just anterior to the implant; more concerning in older silicone devices; consider documenting for surgical discussion.
  • Herniation: smooth focal outpouching through a capsular defect with intact envelope; seen on mammography, US (subtle contour bulge), or MRI (tail-like protrusions).

Implant Rupture: Saline vs Silicone—Clinical and Imaging

Rupture mechanisms include device aging, fold fatigue, surgical/traumatic injury; risk increases with implant age.

Key Points

  • Saline rupture: clinically obvious deflation as saline is resorbed; imaging typically unnecessary unless documenting collapsed shell.
  • Silicone rupture: often clinically silent; mean lifespan ~13 years (augmentation) and ~9–10 years (reconstruction); rupture rates rise markedly after ~10 years.

Intracapsular Silicone Rupture: Imaging Signs

The envelope fails but the fibrous capsule remains intact; most common rupture pattern.

Key Points

  • Mammography: limited for detection; contour often unchanged.
  • Ultrasound: stepladder sign—multiple parallel echogenic lines from folded envelope; distinguish from benign radial folds.
  • MRI:

- Keyhole/teardrop sign: fold containing silicone on both sides (silicone bright internally and externally).

- Linguine sign: multiple curvilinear dark lines (collapsed envelope) floating in bright silicone.

- Increased intraluminal water (dark foci on water-suppressed sequences), especially in double-lumen devices.

Extracapsular Silicone Rupture: Imaging Signs

Both envelope and capsule fail; free silicone escapes into surrounding tissues and nodes.

Key Points

  • Clinical: pain, shape change, contracture, asymmetry; exam detects a subset.
  • Mammography: dense, shaggy free silicone in parenchyma/pectoralis; irregular peri-implant densities; highly calcified, distorted implants may coexist.
  • Ultrasound: snowstorm sign—highly echogenic foci with marked posterior shadowing; silicone “cysts” (more liquid components); echogenic granulomas; hyperechoic lymph nodes.
  • MRI: silicone signal outside the capsule; loss of expected envelope/capsule contours; regional silicone tracking into breast or muscle.

Reporting Pearls and Patient Counseling Considerations

Clear communication improves patient management and expectations.

Key Points

  • State implant type/position when determinable; comment on technical limitations and tissue coverage.
  • Describe classic post-reduction or mastopexy changes to avoid unnecessary workup; use short-interval follow-up when uncertainty exists early post-op.
  • Document capsular calcifications, herniations, malposition, or suspected rupture; recommend MRI for silicone integrity when indicated.
  • Correlate palpable “lumps” over valves or scars with benign implant-related findings when appropriate.

Conclusion

Breast reduction and augmentation produce a spectrum of predictable postoperative findings and device-related complications. Proficient interpretation across mammography, ultrasound, and MRI hinges on understanding surgical techniques, implant construction and position, and hallmark imaging signs such as periareolar scarring, radial folds, stepladder, keyhole/teardrop, linguine, and snowstorm patterns. Consistent technique, precise reporting, and judicious follow-up help differentiate benign postoperative changes from pathology, guide appropriate management, and set realistic expectations for patients with reduced or augmented breasts.